TNPSC Clinical Pharmacology 23 June 2019 Question Paper with Answers Key

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TNPSC Clinical Pharmacology 23 June 2019 Question paper with Answers Key- TNPSC conducted Drugs Inspector in the Tamil Nadu Medical Service & Junior Analyst in the Drugs Testing Laboratory in Tamil Nadu Medical Subordinate Service exam on 23 June 2019 FN from 10.00 AM to 12.30 PM. Here we are providing some of the questions asked in TNPSC Clinical Pharmacology Paper.

Alkaline diuresis is done for treatment of poisoning due to?

Phenobarbitone

Low Vd means……..?

The drug doesnot accumulate in tissues

The chief advantage of the sublingual,route is?

By passes the liner

Carbenicillin and Anti-platelet drug use results in?

Increases risk of bleeding

Nocebo produces……..?

Negative pharmaco dynamic effect

What is pharmacogenetics?

Variability in drug response

Choose the most patent of all the synthetic fentanyl opioid agonists?

Sufentanil

Choose the antipsychotic drug which causes retinal deposits (Browning of vision) a?

Thioridazine

Which parental route of administration has 100% bioavailability?

Intravenous

Device which produce a mist of the drug solution generated by pressurised air?

Jet Nebulizer

Choose the antipsychotic drug with least sedative extrapyramidal side effects?

Ziprasidone

TNPSC Clinical Pharmacology 23 June 2019 Paper

Which combination of drugs are used for rapid opioid detoxification?

Naltrexone + Bupre norphine

……….. are used as nerve gases except?

Dyflos

Acetylcholine is not used commercially because?

Rapidly destroyed in the body

The drug that is contraindicated in angle closure glaucoma is?

Atropine

Which is not an endogenous catecholaminis?

Dobutamine

An ntiarrythmic agent which is also used a calcium channel blocker is?

Verapamie

Which is not used in the treatment of pulmonary hypertension?

Alpha blockers

A suitable estrogen antagonist is?

Clomiphene citrate

Thyrotoxicosis causes……….?

Nodular goitre

The half life of Iodine – 131 is?

8 days

Clinical Pharmacology

TNPSC Clinical Pharmacology 23 June 2019 Questions and answers

The dose of iodine that causes fatal effect is?

3- 4 grams

Gluconeogenesis is promoted by?

Glucocorticoids

Identify a stimulant purgative?

Emodin

The plasma half life of Glipizide is?

3-5 hours

The antacid that causes diarrhoea is?

Magiesium trisilicate

A bulk laxative from plant origin?

Isphagula

A synthetic disaccharide having osmotic purgative action is?

Lactulose

Which is used as Bile acid requerterant?

Cholertyramine

The reason for the a~tion of hepani in cleaning the turbid plasma is?

Releases lipoprotein lipase

Which is given for the treatment of iron poisoning?

Desferrioxamine

TNPSC  Clinical Pharmacology 23 June 2019 paper with  Key

The newer HI blocker having good topical activity is?

Azelastine

Which is not an Antioxidant vitamin?

Vitamin K

Gastric lavage is contraindicated in which type of poisoning?

Acid

Which is a newer synthetic tretinoin like drug?

Adapelene

Which drug targets EG FR in colorectal carcinoma?

Cetuximab

The tetracycline with highest antileprotic activity is?

Minocyclene

Which Anti Retroviral drug inhibits CCR5?

Maraviroc

Inflammation in the airways can be reduced by?

Fluticasone

Bronchodilator of choice in COPD is?

Inhaled anticholinergies

TNPSC Clinical Pharmacology Answers Key 23 June 2019

Analgesic dose of sepirin is?

0.3 to 0.6 gm 6 – 8 hourly

Acute toxicity studies are observed for?

1~ 3 days

What is Reinforcement?

Drug seeking behaviour

Serotonin can be synthesized from?

Tryptophan

Zidovudine (AZT)belongs to the class of?

Anti Viral drugs

Select the antibacterial mechanism of action of Erythromycin?

Inhibition of protein synthesis

Anticancer drug causing SIADM as an adverse affect?

Vincristine

Synthesis of bacterial cell wall is inhibited by?

lactum antibiotics

With which ‘Heat shock protein’ is glucocorticoid receptor associated?

H.S.P 90

Which drug is an inhibition of cytochrome pyro enzymes?

ketoconazole

TNPSC Clinical Pharmacology 23 June 2019 Full Question Paper& Key

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